...to the 12th Sepsis Update of the German Sepsis Society (GSS) “Improving sepsis outcomes: cutting edge in diagnostics & therapy”!

Dear colleagues,

Since the past decades much has been learned to improve sepsis outcomes, yet the condition remains a major cause of morbidity and mortality worldwide. Modulating the dysregulated host response has been hypothesized to advance better sepsis outcomes, but so far, none of the numerous trials on this topic led to the implementation of immunomodulatory sepsis-treatments into day-to-day clinical practice.

New technologies for detection of invading agents and for rapid testing emerge as valuable tools for sepsis diagnostics. Furthermore, multi-omics-based methods help us understand how pathophysiological disturbances that determine sepsis outcomes greatly vary both over time and between individual patients. This provides the groundwork for future identification and stratification of patients based on innovative biomarkers and has the potential to translate into a renaissance of immunetherapies and other tailored treatments.

We are delighted to extend a warm invitation for the upcoming 12th Sepsis Update, which will take place from Thursday 2nd to Saturday 4th October 2025 under the motto `Improving sepsis outcomes: cutting edge in diagnostics & therapy´.

Since 2002, the Sepsis Update held by the German Sepsis Society has emerged as one of the most significant international scientific sepsis meetings. This prestigious event brings together top investigators from around the globe, healthcare professionals and industry partners to discuss the latest advancements, share insights, and collaborate on strategies to provide solutions for sepsis management. In the upcoming 12th Sepsis Update, that will for the first time take place in Heidelberg, the main focus will be on new diagnostics along with innovative therapeutic measures. As program chairs, we look forward to your valuable presence at the Sepsis Update 2025 and to the knowledge and expertise you will bring. Together, we will improve sepsis outcomes!